Finding studies
Finding studies
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Lead
Lantheus Medical Imaging
The primary objectives of this study are: * To acquire data for the development of one-day rest/stress cardiac PET perfusion imaging protocols for BMS747158 with comparable diagnostic image quality to a two-day rest/stress PET protocol * To assess the safety of multiple doses of BMS747158 The secondary objectives of this study are: * To assess PET imaging parameters and image quality following administration of BMS747158 at rest and at stress (pharmacologic or exercise) same day (at different time intervals) and 16-48 hours after the rest injection * To assess feasibility of gated cardiac PET imaging with BMS747158 for left ventricular function assessment * To assess agreement of one and two day rest/stress PET imaging with BMS747158 in patients with reversible ischemia with rest/stress single photon emission computed tomography (SPECT) imaging * To perform a preliminary assessment of the diagnostic accuracy of one-day and two-day rest/stress PET perfusion imaging with BMS747158 as compared with invasive coronary angiography or computed tomography angiography (CTA) for detection of
Age
18–75
Sex
ALL
Healthy volunteers
Not accepted
