Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Lexicon Pharmaceuticals
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Males and females ≥ 18 years old
Must be willing to practice 2 adequate methods of contraception for the duration of the study
Rheumatoid arthritis present for at least 3 months; functional class I, II, or III as defined by ACR criteria
Treatment with methotrexate (7.5 to 25 mg per week) for at least the last 3 months, and currently receiving stable dose methotrexate for at least one month prior to the start of the study
Ability to provide written informed consent
You may not be if
Women who are pregnant or nursing
History of other current inflammatory arthritis
History of opportunistic infection
History of recurrent infections or current infection 2 weeks prior to start of study
Presence of significant, uncontrolled medical problems
Treatment with any disease-modifying anti-rheumatoid drugs other than methotrexate within 4 weeks prior to start of study
Use of chondroitin sulfate, glucosamine sulfate, minocycline, or matrix metalloproteinase inhibitors, H-2 blockers, proton pump inhibitors, or misoprostol within 4 weeks prior to study start
Receipt of live vaccine within 8 weeks prior to study start
Rheumatoid arthritis, functional class IV as defined by ACR criteria
