Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Massachusetts, Worcester
Asthma is a pulmonary disorder that affects millions of people each year. The exact method of exacerbation is still under some discussion. Currently there is no cure for the disorder but treatment is of a wide variety.
This study is meant to image the asthmatic lung at various time points post exacerbation. Since pulmonary imaging is currently limited to radiation techniques, this method will allow exacerbated images without the unnecessary exposure to radiation.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
At least 18 years old
Able to speak and read English
Acute asthma exacerbation, defined as requirement for hospitalization or emergent outpatient visit, and treatment with high dose corticosteroids ( 40mg prednisone or equivalent)
FEV1 \< 80% predicted on the day of MRI
Attending physician agrees that patient is safe to participate on the day of the MRI scan
You may not be if
Evidence of pneumonia, based on chest radiograph obtained within 24 hours of enrollment (if performed)
Documented fever or requirement for antibiotics
Unable to hold breath for 10 seconds
Active smoker or history of at least 10 pack years cigarette smoking
Chest radiograph with active pulmonary disease, except for changes expected with asthma (hyperinflation, subsegmental atelectasis)
Admission to ICU
For inpatients: contraindication to leaving hospital room for MRI as determined by Attending physician and RN on day of MRI
Any other concurrent active pulmonary disease or other unstable or active medical condition (including suspected active coronary ischemia, acute bleeding), as determined by Attending physician
Pregnancy as self reported
Need for cardiac monitoring
Need supplemental oxygen at an amount of 4L/min or a facemask
Clareo Health | Asthma Exacerbation and Helium-3 MRI
