Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Chicago
Study Objectives:
Primary Objective: To assess the impact of ciprofloxacin on the change in PSA from baseline/randomization to prostate biopsy
Secondary Objective: To assess the impact of ciprofloxacin on the overall infectious complications following prostate biopsy
The impact of observation versus ciprofloxacin on PSA levels will be assessed by PSA change from baseline. The first PSA measurement will be at the study entry and randomization. The second PSA measurement will be immediately prior to prostate biopsy, which will occur 21-45 days following randomization.
Age
18–any
Sex
MALE
Healthy volunteers
Not accepted
You may be eligible if
Men 18 yrs. or older
An elevated PSA (\>2.5 ng/ml) and normal digital rectal exam
Have elected to proceed with a diagnostic 12-core prostate biopsy
You may not be if
Previous prostate biopsy
History of prostate cancer
Urinary tract infections or prostatitis within one year of study entry
antibiotic use within one month prior to PSA level
pyuria or bacteruria on urinalysis
allergy to fluoroquinolones
Clareo Health | Randomized Trial of Ciprofloxacin Versus Observation for Men With Elevated Prostate Specific Antigen (PSA)
