Trial of Belotecan/Cisplatin in Chemotherapy Naive Small Cell Lung Cancer Patient

Exclusion Criteria

• •As judged by the investigator, any evidence of severe or uncontrolled systemic disease
• •Serum bilirubin greater than 3 times the upper limit of reference range(ULRR)
• •Aspartate aminotransferase (AST/SGOT) or alanine aminotransferase (ALT/SGPT)greater than 2.5 times ULN if no demonstrable liver metastases (or \> 5 times in presence of liver metastases)
• •Evidence of any other significant clinical disorder or laboratory finding that makes it undesirable for the subject to participate in the study
• •Pregnancy or breast-feeding women(women of child-bearing potential). Women of childbearing potential must practice acceptable methods of birth control to prevent pregnancy
• •Evidence of brain metastasis