Age

18–any

Sex

ALL

Healthy volunteers

Not accepted

knee pain, aching or stiffness on most of the past 30 days
x-ray verified predominant medial tibiofemoral osteoarthritis (TFOA)
overall pain that is due to the medial TFOA (versus being referred from the back, hips, or other pre-existing conditions)
ambulatory persons

use of a crutch, walker, or wheelchair or cane more than 50% of the time
history of Deep Vein Thrombosis
Pain emanating more from back or hip than from knee
Low pain score on WOMAC
predominant patellofemoral disease or knee pathology other than medial compartment OA likely to be causing their knee pain.
Planning to move from area within 1 month of study screening.
Unable to fit the brace properly
BMI greater than 35
corticosteriod injections in the past month
Bilateral total knee replacements or plan for TKR
Other types of arthritis including Rheumatoid Arthritis, Systemic Lupus Erythematosus, gout, psoriatic arthritis, pseudogout.
woman who are pregnant (due to x-rays taken to determine eligibility)

Mechanics of Knee Bracing