Sponsors

Lead Sponsor

The University of Texas Health Science Center, Houston

Age

35 - 70 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•1. 35-70 year old men \& women
•2. (1) Diagnosis of idiopathic RBD (see AASM criteria), 2) Normal control or control with a non-neurodegenerative disorder, age and gender-matched to (1)
•3. Gives written informed consent
•4. Pregnant women are not excluded, but will be identified by HCG.

Exclusion Criteria

•a A diagnosis of any non-Parkinsonian Neurodegenerative Disease.
•b. Any unstable or uncontrolled medical or psychiatric condition.
•c. Parasomnia or RBD not idiopathic, eg., secondary to metabolic derangement or medicine effect.
•d. Renal (creatinine over 1.6) or hepatic insufficiency (LFT significantly out of range), or a history of significant uncontrolled cardiac disease.
•e. Significant dementia (MMSE\<25 of 30 or MOCA\<25/30) that would interfere with study procedures or informed consent.
•f. Any reason which, in the opinion of the PI, would increase the risk or decrease the value of any study procedure.
•g. fMRI will not be performed for anyone for whom the screening questionnaire indicates is ineligible for MRI imaging.

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What this study is about

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Sponsors

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Trial snapshot

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For caregivers