Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Organon and Co
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Patient has a history of migraine with or without aura for more than one year, with between 2 and 8 moderate to severe attacks per month
Patient is currently taking at least 50 mg topiramate daily for migraine prophylaxis
Patient can distinguish between migraine and other types of headache
Patient agrees to remain abstinent or use effective birth control during the study
You may not be if
Patient is pregnant or breast-feeding
Patient has a history of mostly mild migraines or migraines that resolve within 2 hours
Patient has more than 15 headache-days per month or has taken medication for acute headache on more than 10 days per month in the 3 months prior to screening.
Patient was \> 50 years old at age of migraine onset
Patient has history of heart disease
Patient has uncontrolled hypertension
Patient has had cancer within 5 years of screening (excepting certain skin and cervical cancers)
Patient has started taking Selective Serotonin Reuptake Inhibitors (SSRIs) or Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs) or has changed doses within 3 months of screening
Patient is taking more than one other migraine prophylactic medication
Patient has repeatedly failed to respond to or tolerate rizatriptan
Clareo Health | A Study of Rizatriptan for the Treatment of Acute Migraine in Patients on Topiramate for Migraine Prophylaxis