Primary Vaccination Study With a Pneumococcal Conjugate Vaccine in Healthy Children 6-12wks of Age

Exclusion Criteria

• •Use of any investigational or non-registered product (drug or vaccine) other than the study vaccines within 30 days preceding the first dose of the study vaccines, or planned use during the study period.
• •Concurrently participating in another clinical study, at any time during the study period.
• •Chronic administration (defined as more than 14 days) of immunosuppressants or other immune-modifying drugs since birth.
• •A family history of congenital or hereditary immunodeficiency.
• •Any confirmed or suspected immunosuppressive or immunodeficient condition based on medical history and physical examination.
• •Administration of immunoglobulins and/or any blood products since birth or planned administration during the study period (with the exception of hepatitis B immunoglobulins at birth).
• •Previous vaccination against diphtheria, tetanus, pertussis, poliomyelitis, hepatitis B, Haemophilus influenzae type b and/or Streptococcus pneumoniae (with the exception of vaccines where the first dose can be given within the first two weeks of life).
• •Planned administration/administration of a vaccine not foreseen by the study protocol during the period starting 30 days before each dose of vaccine and ending 7 days after Dose 1 and Dose 2 and 30 days after Dose 3.
• •History of, or intercurrent diphtheria, tetanus, pertussis, hepatitis B, poliomyelitis, H. influenzae type b and rotavirus disease.
• •History of allergic disease or reactions likely to be exacerbated by any component of the vaccines.
• •History of any neurological disorders or seizures.
• •Major congenital defects or serious chronic illness.
• •Acute disease at the time of enrolment.
• •Gastroenteritis within 7 days preceding the study vaccine administration.
• •Any clinically significant history of chronic gastrointestinal disease including any uncorrected congenital malformation of the gastrointestinal tract, intussusception or other medical condition determined to be serious by the investigator.