prior chemotherapy or treatment with another systemic cancer therapy;

surgery (including open biopsy), significant traumatic injury, or radiotherapy within the last 4 weeks prior to first dose of study treatment;

brain metastasis or spinal cord compression;

fertile men, and women of childbearing potential, not using adequate contraception;

treatment with any other investigational agent, or participation in another clinical trial, within 30 days prior to entering the study.

A Study of Avastin (Bevacizumab) in Patients With Non-Squamous Non-Small Cell Lung Cancer (NSCLC)