PASCAL Trabeculoplasty

Semi-Automated Patterned Laser Trabeculoplasty

NCT00804323•Asociación para Evitar la Ceguera en México

Summary

Argon laser trabeculoplasty (ALT) with 100 ms pulses is an effective therapy for lowering intraocular pressure (IOP). Similar reductions in IOP have been achieved using ns (SLT) and microsecond (MLT) pulses, which produce less thermal damage to trabecular meshwork (TM). Lack of clinically visible changes may make the accurate alignment of subsequent pulses difficult. We describe a novel technique - Patterned Laser Trabeculoplasty (PLT) using the PASCAL Photocoagulator system, and its preliminary evaluation in patients with open angle glaucoma.

Eligibility

Age

18 - 90 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•18-year-old patients
•Uncontrolled Open angle (Shaffer IV)
•No previous surgical trabeculoplasty or glaucoma surgery

Exclusion Criteria

•Patients not willing to participate
•Angle-closure glaucoma
•No clear optical media

Locations (1)

Asociación para Evitar la Ceguera en México

Mexico City, Mexico City, Mexico

Key Dates

Start Date

December 1, 2007

Primary Completion Date

December 1, 2008

Completion Date

December 1, 2009

Last Updated

May 30, 2024

Enrollment

ACTUAL participants

Conditions

Open-Angle Glaucoma

Interventions

Patter Scan Laser System (OptiMedica, Santa Clara, CA, USA)

PROCEDURE

A Randomized, Double-blind, Parallel-group, Two-arm, Multiple Dose, Multicenter, Bioequivalence Study With Clinical Endpoint in the Treatment of Subjects With Chronic Open-angle Glaucoma or Ocular Hypertension in Both Eyes

NCT06267274

Open-angle GlaucomaOcular Hypertension

View study

COMPLETEDPHASE3

Evaluation of the Duration of Effect of Bimatoprost SR in Participants With Open-Angle Glaucoma or Ocular Hypertension

NCT03850782

Open-Angle GlaucomaOcular Hypertension

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: May 30, 2024Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

PASCAL Trabeculoplasty

Inclusion Criteria

Exclusion Criteria

A Randomized, Double-blind, Parallel-group, Two-arm, Multiple Dose, Multicenter, Bioequivalence Study With Clinical Endpoint in the Treatment of Subjects With Chronic Open-angle Glaucoma or Ocular Hypertension in Both Eyes

Evaluation of the Duration of Effect of Bimatoprost SR in Participants With Open-Angle Glaucoma or Ocular Hypertension

PRESERFLO® MicroShunt Extension Study

Study Comparing the Effects of Latanoprostene Bunod and Timolol on Retinal Blood Vessel Density and Visual Acuity

Subjects With Open-angle Glaucoma, Pseudoexfoliative Glaucoma, or Ocular Hypertension Naïve to Medical and Surgical Therapy, Treated With Two Trabecular Micro-bypass Stents (iStent Inject) or Travoprost

Efficacy and Safety Outcomes of Optometrist Performed Selective Laser Trabeculoplasty (SLT)