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Keep this study
Lead
Vanderbilt University Medical Center
The purpose of this study is to look at certain areas of the brain that are related to addictive behaviors, such as overeating. These areas are called 'dopamine type 2 receptors' (DRD2/3) and other studies have shown that obese people have less of these. We propose that low DRD2/3 availability seen in morbidly obese subjects will change with weight loss associated with bariatric surgery.
Age
18–60
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Ages 18-60 years
BMI equal to or greater than 40, or equal to or greater than 35 if there are 2 or more co-morbidities
Weight less than 350 pounds
You may not be if
History of substance abuse,including but not limited to alcohol, cocaine, marijuana, heroin, nicotine
History of psychiatric disorders
Use of any antidepressants or psychotropics in the past 12 months
Diabetes Mellitis
Positive pregnancy test
Any condition felt by the PI or co-investigators to interfere with the individual's ability to complete the study
Subjects on medications for the last 3 months, such as sibutramine, which could affect the quality of the study, as determined by the PI
