* Anaplastic large-cell lymphoma (Ki1+, B-, T- oder Null-cell-type)
* Mediastinal large B-cell-lymphoma (subtype of diffuse large B-cell lymphoma)
Age = 18 years
Patient's Informed Consent
You may not be if
Serious complications caused by leukemia/ lymphoma or by a second illness: e.g.
* Severe, unmanageable complications such as sepsis, pneumonia with oxygen deficiency,
* Shock, hemorrhage at the time of diagnosis
* Renal insufficiency from leukemia/lymphoma-unrelated causes
* Severe cardiac or hepatic insufficiency
* Severe obstructive or restrictive lung disease that would compromise patient's treatment with intensified chemotherapy
* HIV infection
* Secondary lymphoma following prior chemotherapy/ radiotherapy or an active second malignancy
* Known severe allergy to foreign proteins
Cytostatic pretreatment for B-ALL/lymphoma (exceptions: short-term administration of steroids = 7 days, single administration of vincristine or cyclophosphamide, one cycle of CHOP, a single administration in an emergency of other cytostatic agents) for another malignant disease within the last 5 years
Pregnancy/ nursing period
Severe psychiatric illness or other circumstances giving ground to the assumption that a patient cannot give his consent to therapy or act co-operatively
Absence of patient's informed consent
Participation in another clinical study that would possibly interfere with study therapy
Clareo Health | Intensification Therapy of Mature B-ALL, Burkitt and Burkitt Like and Other High Grade Non-Hodgkin's Lymphoma in Adults
