Lead Sponsor

Wyeth is now a wholly owned subsidiary of Pfizer

Age

18 - 99 years

Sex

ALL

Healthy Volunteers

Yes

•Men or women aged 18 - 50 years (healthy subjects) or greater than 55 years old (subjects with Alzheimer's Disease)
•Women must be surgically sterile or postmenopausal
•Subjects with Alzheimer's Disease must be generally healthy, but may have a stable, chronic illness if well controlled.

•Healthy subjects may not be on any prescription or investigation drugs within 30 days of start of study.
•Subjects with Alzheimer's Disease may not be on any cholinesterase inhibitors such as donepezil (Aricept®) or rivastigmine (Exelon®) within 4 weeks of the start of the study.