Lead Sponsor

Novartis

Age

40 - 85 years

Sex

ALL

Healthy Volunteers

No

•Male and/or female patients between 40 and 85 years of age (both inclusive)
•Diagnosis of mild Alzheimer's Disease (AD)
•Mini-Mental State Examination (MMSE) 20 to 26 at screening, untreated or on stable dose of cholinesterase inhibitor or memantine over the last 6 weeks.

•Previously participated in an AD vaccine study and received active treatment.
•History or presence of an active autoimmune and/or with an acute or chronic inflammation, and/or clinically relevant atopic condition.
•History or presence of seizures and/or cerebrovascular disease.
•Presence of other neurodegenerative disease and/or psychiatric disorders (with the exception of successfully treated depression)
•Advanced, severe, progressive or unstable disease that might interfere with the safety of the patient.