Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Yale University
With
Ethel F. Donaghue Women's Health Investigator Program at Yale
Age
18–70
Sex
FEMALE
Healthy volunteers
Not accepted
You may be eligible if
Women between the ages of 18 to 70
Meet DSM-IV (Diagnostic and Statistical Manual version IV) criteria for schizophrenia or schizoaffective disorder based on SCID (Structured Clinical Interview for the DSM-IV) interview
Overweight, as defined with a BMI of equal to or greater than 27 kg/m² and continuing weight gain in the past year above 2% of previous years total body weight
Be on a stable dose of antipsychotic medication; i.e. at least one month with no dosage change, and two months from an antipsychotic switch; 5) Deemed to be symptomatically stable by the clinical staff in the last two months
You may not be if
Meet criteria for current alcohol or other substance dependence, opioid use for any reason or positive urine drug screen for opiates
A history of dementia, mental retardation or other neurological disorder that may interfere with study ratings
Not capable of giving informed consent for participation in this study
Ongoing pregnancy
Known sensitivity to naltrexone
A medical disorder that is known to cause obesity
Use of sibutramine, topiramate, amphetamines or over the counter weight remedies
Impaired liver functions (greater than 3 times the upper limit of normal)
Diagnosed with polycystic ovary syndrome
Currently being treated with insulin
Current use of Depo-Provera or any natural/synthetic hormone treatment known to cause significant weight gain
