Pre-surgery image staging as (CT/MRI):T2-3,N0-2,M0,(TNM stage，AJCC，version of 2003)
Single tumor locating at cecum, ascending colon, descending colon, sigmoid colon, rectosigmoid junction, rectum(distance from anal verge more than 7cm)
Tumor diameter less than 6cm
Age 18-75 year
ECOG 0-2
Predicted survival longer than 6 months
Normal liver, renal, bone marrow function: (GPT less than 2 ULN，total bilirubin less than 1.5mg/dl，Cr less than 1.5 ULN，WBC more than 4×109/L，PLT more than 100×109/L)
No previous history of gastrointestinal surgery
No previous history of chemotherapy or radiotherapy
You may not be if
Severe and uncontrolled medical disease including unstable angina pectoris, cardiac infarction and cerebral attack in 6 months
Could not tolerant general anesthesia or surgery for other organ dis-function
Allergy to chemotherapeutical agents in the protocol
