Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Tampa General Hospital
With
CSL Behring
Patients with high level of preformed antibodies (panel reactive antibodies \[PRA\]) to donor antigens make identification of a suitable donor difficult. For most transplant centers, 20-35% of patients waiting for a kidney transplant comprise this challenging group. These patients have a wait time of over five years and have many incompatible cross-matches with potential organ donors.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Renal transplant recipients with a potential living donor who is incompatible (T-\&/or B-cell locus) due to recipient high PRA or MHC antibodies
PRA greater than or equal to 20% within last twelve months
Recipient and donor accepted as potential candidates by the LifeLink Healthcare Renal Transplant Committee
You may not be if
Patients with known allergy to CytoGam(R), Cellcept, Rapamycin
Patients who will receive IVIG or CytoGam(R) for any cause prior to protocol process
ABO incompatibility
Patients not capable of following through the treatment for various reasons as determined by treating physicians
Any potential recipient who is pregnant or becomes pregnant
Exclusion for Plasmapheresis: known allergy to ethylene oxide or natural rubber latex.
Exclusion for Plasmapheresis: Intake of ACE-inhibitor or Angtiotensiin-receptor blockers in the last 24 hours prior to plasma exchange
