Complete Occlusion of Coilable Aneurysms

Exclusion Criteria

• •Target IA has BOTH neck \>4 mm AND size (maximum fundus diameter) \>10 mm
• •More than one IA requires treatment in the next 6 months
• •Subarachnoid hemorrhage in the past 60 days
• •Any intracranial hemorrhage in the last 42 days
• •Major surgery in the last 42 days
• •Coils in place in the target IA
• •Unstable neurologic deficit (i.e., any worsening of clinical condition in the last 30 days)
• •Known irreversible bleeding disorder
• •Platelet count \< 100 x 103 cells/mm3 or known platelet dysfunction
• •Inability to tolerate, documented evidence of adverse reaction or contraindication to study medications
• •Prior stent placement at target site
• •Contraindication to CT scan AND MRI
• •Known allergy to contrast used in angiography that cannot be medically controlled
• •Known severe allergy to platinum or cobalt/chromium alloys
• •Relative contraindication to angiography (e.g., serum creatinine \> 2.5 mg/dL)
• •Woman of child-bearing potential who cannot provide a negative pregnancy test
• •Evidence of active infection at the time of treatment
• •Other known conditions of the heart, blood, brain or intracranial vessels that carry a high risk of neurologic events (e.g., severe heart failure, atrial fibrillation, known carotid stenosis)
• •Current use of cocaine or other illicit substance
• •Any comorbid disease or condition expected to compromise survival or ability to complete follow-up assessments to 180 days
• •Extracranial stenosis greater than 50% in the carotid artery
• •Intracranial stenosis greater than 50% in the treated vessel