Specific aims:
1. To study biology of wound derived inflammatory cells and fluid from diabetic versus non diabetic wounds.
2. To characterize mechanisms that are responsible for dysregulated wound inflammatory cell function in individuals with diabetes.
3. To characterize differences in the biology of normal peripheral blood derived cells versus wound derived cells.
The long-term goal of this study is to determine the molecular mechanisms underlying impaired wound healing in diabetics.
Age
21–80
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Ages 21-80
Chronic Wound (present \>4 weeks)
Diabetic \& Non-diabetic
Adult surgical wounds
You may not be if
Inability to consent
Pregnant women
Therapeutically immunocompromised
Individuals defined in 45 CFR 46 Subparts B,C, and D, nor from any other population considered vulnerable 2.9
Clareo Health | Mechanisms Underlying Impaired Diabetic Wound Healing