A Randomised Controlled Trial of the Use of Topical Metronidazole (10%) to Reduce Pain After Haemorrhoidectomy

Inclusion Criteria

• •Have Grade 3 or 4 haemorrhoids (external disease with or without significant internal component)
• •Be scheduled for diathermy haemorroidectomy with ≥2 quadrant involvement
• •Be medically fit for surgery
• •Subjects must be aged 18 years or over and of the legal age of consent.
• •If female, the subject must not be lactating and must be (a) post-menopausal, (b) surgically sterilised, or (c) have a negative pregnancy test result prior to entry into the study and will use adequate contraception for the duration of the study.
• •Must have provided written informed consent to participate.