Lead Sponsor

Colgate Palmolive

Age

20 - 51 years

Sex

ALL

Healthy Volunteers

Yes

•Male or female volunteers at least 20 - 51 years of age
•Good general health
•Must sign informed consent form
•Minimum of 15 natural uncrowned teeth (excluding third molars) must be present
•No history of allergy to personal care consumer products, or their ingredients, relevant to any ingredient in the test products as determined by the dental/medical professional monitoring the study

•Subjects unable or unwilling to sign the informed consent form
•Medical condition which requires pre-medication prior to dental visits/procedures
•Moderate or advanced periodontal disease or heavy dental tartar (calculus)
•5 or more decayed untreated dental sites at screening (cavities)
•Other disease of the hard or soft oral tissues.
•Impaired salivary function (e.g. Sjogren's syndrome or head and neck irradiation).
•Use of medications that are currently affecting salivary function
•Use of antibiotics or antimicrobial drugs within 30 days prior to study visit #1
•Pregnant or nursing women
•Participation in any other clinical study within 1 week prior to enrollment into this study
•Use of tobacco products
•Subjects who must receive dental treatment during the study dates
•Current use of Antibiotics for any purpose
•Presence of an orthodontic appliance which interferes with plaque scoring
•History of allergy to common toothpaste ingredients
•History of allergy to arginine (amino acid)
•Immune compromised individuals (HIV, AIDS, immuno suppressive drug therapy)