Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Witwatersrand, South Africa
Age
18–55
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
HIV infected adult on stable first line HAART for more than 3 months or anti-retroviral naïve HIV infected adult with a CD4+ cell count \>100 cells/ml performed within the previous 3 months in relation to the date of randomization.
Age 18-55 years.
Willing and able to maintain weekly contact at least during period of April - August (i.e. presupposed influenza period) either through SMS or telephonic contact.
Willing and able to adhere to study protocol re: attendance to clinic for scheduled and illness visits.
You may not be if
Any contraindication to influenza vaccination, including known allergy to egg.
Currently on treatment for tuberculosis or received treatment for tuberculosis in the past 6 months.
History of chronic lung disease which required maintenance therapy either currently or in the past 6 months.
Any contraindication to intramuscular injections.
Current known grade 3 or grade 4 laboratory or clinical toxicity as per DAIDS toxicity tables.
Any previous history of influenza or pneumococcal vaccination.
Any plan to vaccinate against influenza or pneumococcal disease during the course of the study.
Plan to emigrate from the study area within the next year.
On steroid therapy for \>21 days (current or within the past 30 days).
In the investigators opinion unable to maintain study procedures.
