Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Baylis Medical Company
Back Pain
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
* Age 18 + years
* History of chronic low back pain unresponsive to nonoperative care (including physical therapy and anti-inflammatory medication) for longer than 6 months of at least 5 on VAS
* No surgical interventions within the last 3 months
* Back pain more than leg pain which is commonly exacerbated by sitting
* Pain reproduction present on provocative discography in degenerated disc but not in control discs
* Disc height at least 50% of adjacent control disc
* Evidence of single level degenerative disc disease or two level disease without evidence of additional degenerative changes in other disc spaces on MRI
You may not be if
* Evidence of compressive radiculopathy with predominant leg pain
* Nucleus pulposus herniation on the MRI
* Disc bulges \> 5 mm
* Prior lumbar surgery of any kind
* Presence of concordant cervical or thoracic pain
* Symptoms or signs of the lumbar canal stenosis
* Evidence of structural abnormality at the symptomatic level like spondylolisthesis
* Chronic severe conditions such as rheumatoid arthritis and fibromyalgia
* Patients with pending workers compensation claim, litigation or disability income remuneration
* Psychological issues by exam or history
* Beck Depression Inventory (BDI) \>20
* Pregnancy
* Systemic infection or localized infection at the anticipated entry needle site
* Allergies to contrast media or to any medication to be used in the procedure
* Traumatic spinal fracture
* History of coagulopathy, unexplained bleeding
* Progressive neurological deficits
* History of opioid abuse
* Presence of free disc fragments on MRI
* More than 2 discs degenerated on MRI
* Immunosuppression (eg. AIDS, cancer, diabetes, other surgery within last 3 months)
* Smoking
* BMI (body mass index) \>30 kg/m2
* Subject unwilling to consent to the study
* Participation in another investigation within 30 days of signing informed consent
