Study to Explore the Effect of Mefloquine in Participants With Progressive Multifocal Leukoencephalopathy (PML)

Exclusion Criteria

• •Other opportunistic infection of the central nervous system.
• •Current severe illness or any other conditions that, in the opinion of the Investigator, would make the subject unsuitable for enrollment.
• •Active severe mental illness (e.g., depression, anxiety, psychosis, and schizophrenia).
• •Hypersensitivity to mefloquine, quinine, or quinidine, or to any component of these drugs.
• •Current treatment with quinine, quinidine, chloroquine, or halofantrine.
• •Note: Other protocol-defined criteria may also apply.