Fluconazole Prophylaxis for the Prevention of Candidiasis in Infants Less Than 750 Grams Birthweight

Exclusion Criteria

• •History of a hypersensitivity or severe vasomotor reaction to any azole
• •receiving antifungal therapy for suspected/proven invasive fungal infection
• •medical condition, in the opinion of the Investigator, may create an unacceptable additional risk
• •diagnosed with invasive candidiasis or congenital Candida infection.
• •liver failure (AST and ALT \> 250 U/L)
• •renal failure (creatinine \> 2 mg/dL)
• •major lethal congenital or genetic anomalies
• •triplet or higher multiple gestations