Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Pfizer
Age
18–99
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Osteoarthritis of the knee according to ACR criteria with a Kellgren-Lawrence x-ray grade of 2.
Unwilling or unable to take non-opiate pain medications, for whom non-opiate pain medications have not provided adequate pain relief or are candidates for knee injections arthroplasty or replace surgery.
Pain level and function levels as required by the protocol at Screening and Baseline.
Willing to discontinue pain medications (acetaminophen will be permitted up to a certain level) before and during the study.
Must agree to the contraceptive requirements of the protocol if applicable.
Must agree to the treatment plan, scheduled visits, and procedures of the protocol.
You may not be if
Pregnancy or intent to become pregnant during the study
BMI greater than 39
other severe pain, significant cardiac, neurological or psychological conditions, or above the protocol limits for laboratory and blood pressure results
