Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
R-Pharm
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Histologically confirmed non-small cell lung cancer (NSCLC)(squamous cell, adenocarcinoma, large cell, or bronchoalveolar carcinoma)
Stage IIIB NSCLC with pleural effusion, Stage IV NSCLC, or recurrent disease following surgery with or without radiation therapy
Available paraffin-embedded tissue to measure the expression levels of βIII tubulin
Disease measurable by Response Evaluation Criteria in Solid Tumors, with at least 1 target lesion situated outside any previous radiotherapy field
Karnofsky performance status of 70-100
Life expectancy of at least 3 months
Men and women, ages 18 years and older
You may not be if
Uncontrolled brain metastases
Peripheral neuropathy greater than Grade 1
Fewer than 4 weeks from prior radiation therapy or locoregional surgeries to randomization date (less than 1 week from focal/palliative radiotherapy or minor surgery)
Any concurrent malignancy other than nonmelanoma skin cancer or carcinoma in situ of the cervix
Known HIV-positive status
Absolute neutrophil count lower than 1500 cells mm\^3
Total bilirubin level higher than upper limit of normal (ULN) as defined by the institution (with the exception of elevation due to Gilbert's syndrome)
Aspartate transaminase or alanine transaminase level higher than 2.5\*ULN
Serum creatine level of 1.5 mg/dL or higher
Renal function with a creatinine clearance of less than 50 mL/min (as calculated with the Cockcroft and Gault equation)
