Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
McMaster University
With
Canadian Institutes of Health Research (CIHR)
Age
18–75
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
1. Be \>= 18 years of age
2. Have had ONE episode of unprovoked proximal DVT and/or PE
3. Have completed 3 uninterrupted months of warfarin therapy (target INR of 2.0-3.0)
You may not be if
1. Another indication for long-term anticoagulation (e.g., atrial fibrillation)
2. A high risk of bleeding as evidenced by any of the following:
* Age greater than 75 years
* Previous episode of major bleeding where the cause was not effectively treated
* Known chronic thrombocytopenia with a platelet count of less than 120,000 x 10\^9 /L
* Known chronic renal impairment with a creatinine of more than 150 mumols /litre (1.7 mg/dl)
* Known chronic liver disease with a total bilirubin of more than 25 mumols /litre (1.5 mg/dl)
* Active peptic ulcer disease
* Poor compliance with, or control of, anticoagulant therapy during initial treatment
* Requires dual antiplatelet therapy (e.g. aspirin and clopidogrel)
3. A vena caval filter
4. Has had D-dimer testing performed within 2 months of potential enrollment other than for evaluation of suspected recurrent VTE that was not confirmed
5. Has a life expectancy less than 5 years
6. Is unable to attend follow-up visits because of geographic inaccessibility
7. Is participating in a competing clinical investigation
