Effectiveness of the Eradication of Helicobacter Pylori and an Inhibitor of Pump With Proton Versus Control

Exclusion Criteria

• •treatment by anti-coagulant, whatever its nature and its posology, by proton pump inhibitor, H2 receptor antagonists or antiacid having to be continued beyond the day of inclusion
• •Treatment by methotrexate in progress or stopped since less 3 months.
• •Time of more 7 months enters the beginning of the treatment by aspirin and the visit of inclusion
• •Treatment by NSAID (even occasional or self medication) under or stopped since less 3 months.
• •Treatment by anti-platelet drug (clopidogrel, ticlopidine, flurbiprofen, dipyridamole or antagonist of receptor GPIIb/IIIa) in progress or stopped since less than 10 days.
• •Patient with a serious pathology compromising survival in the 6 month to come.
• •Patient with renal or respiratory insufficiency or a hepatic pathology having a clinical repercussion.
• •History of surgery of esophagus, stomach or duodenum.
• •History of digestive tract bleeding or gastro-duodenal ulcer or esophagal ulcerating proven by endoscopy.
• •Allergy known to clarithromycin.
• •Psychiatric disorder not controlled by treatment.
• •Patients all ready include in a therapeutic protocol or to be followed for 6 month.
• •Alcohol consumption higher than 100gr. per day.
• •Patient non suitable for participating in the protocol or to be followed for 6 month.
• •History of intolerance to salicylate.
• •Constitutional or acquired hemorrhagic disease
• •Pregnant woman or nursing.
• •Patient in emergency, people hospitalized without their assent, people without freedom, people without social health insurance.