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Long Term Follow up of Nasolacrimal Intubation in Adults With Mild Epiphora
For patients with chronic epiphora, Dacryocystorhinostomy is currently the gold standard treatment, with a success rate of 80-90% according to literature. Another available treatment, which is far less used, in nasolacrimal intubation, using a silicone tube. In our study, we would like to find the efficacy of nasolacrimal duct intubation, which was performed in our medical center on a few hundred patients with mild epiphora. Study hypothesis: nasolacrimal intubation in adults, with a clinically mild epiphora, is close in it's efficacy to the Dacryocystorhinostomy procedure.
Under normal conditions, the amount of tears excreted from lacrimal glands to the eye is equal to the amount drained through the tear duct. Epiphora in adults usually involves a blockage of the lacrimal sac or the nasolacrimal duct. Epiphora causes tearing in patients, which can be treated sympthomatically in a conservative way (antibiotic treatment, probing of the tear duct, pressure irrigation of the tear duct) or therapeutic in an invasive way. The invasive treatment includes one of the following: 1. Dacryocystorhinostomy - surgery for reconstructing an alternative path for tear drainage. 2. Nasolacrimal intubation - inserting a silicone tube through the tear duct. The tube is usually removed after 3-6 months. Currently, there are only a few reports regarding the efficacy of nasolacrimal intubation, all with a small number of research subjects. Also, these reports have stratified the patients according to the location of the tear duct blockage, and didn't take into account the severity of the blockage (ie the severity of symptoms) prior to performing the intubation. In our research, we would like to find the efficacy of nasolacrimal intubation which was performed in our medical center on a few hundred patients with mild epiphora, and to compare in with the efficacy of the Dacryocystorhinostomy - which is 80-90% according to literature.
Age
18 - 75 years
Sex
ALL
Healthy Volunteers
No
Maccabi Healthcare Eye Clinic
Tel Aviv, Israel
Start Date
January 1, 2000
Primary Completion Date
December 1, 2007
Last Updated
June 27, 2008
180
ACTUAL participants
Silicone tube
DEVICE
Lead Sponsor
Shaare Zedek Medical Center
NCT06551766
NCT04968561
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View ClinicalTrials.gov Terms and ConditionsNCT03436576