Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Sanofi
Age
18–75
Sex
MALE
Healthy volunteers
Not accepted
You may be eligible if
Histological or cytological confirmation of prostate adenocarcinoma
Advanced prostate carcinoma.
Previous treatment with hormones
Levels of testosterone \< 50 ng/dL
Good hematological, liver and kidney function
Previous treatment with surgery or radiotherapy, at least 4 weeks since end of treatment is allowed (the patient should have been recovered from any side effects.
You may not be if
Previous chemotherapy (estramustine included).
Second line hormonotherapy (oestrogens, gestagens, ketoconazole, ...included)
Previous treatment with radiotherapy (isotopes) or previous radiotherapy over \> 25% of the marrow
Any malignant process with a free disease interval under 5 years, exception done to non-melanoma skin cancer.
Concomitant serious diseases
Concomitant treatment with any other neoplassic therapy (exception done to LHRH agonists and/or biphosphonates).
Contraindication for the treatment with estramustine.
Previous history of pulmonary embolism, thromboembolic disease, previous treatment with anticoagulants (except aspirin), active thrombophlebitis or hypercoagulation.
Previous history of pulmonary spillage or ascitis.
The above information is not intended to contain all considerations relevant to a patient's potential participation in a clinical trial.
