Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Pfizer
Study was terminated on January 20, 2009 due to portfolio decision by Pfizer to discontinue further investigation of PD200390 for non-restorative sleep. The decision was not based on any safety concerns.
Age
18–64
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Subjects who self report nonrestorative sleep but no problems either getting to sleep or staying asleep
Complaints of significant distress or impairment in social, occupational, or other important areas of functioning during daytime for at least 3 nights per week
Self reports sWASO (Wake after sleep onset) for \<45 minutes for past 3 months, self reports LPS (latency to persistent sleep onset ) for \<20 minutes for past 3 months (then neither PSG (polysomnography) screening night showing WASO \>45min, or LPS \> 20 minutes)
Customary bedtime betw. 9 pm and midnight and rise between 4 and 9 AM
You may not be if
Psychiatric disease or disorder as determined by current administration of the MINI (Mini International Neuropsychiatric Interview)
History or presence of any breathing-related sleep disorder, narcolepsy, or any other dyssomnias or any parasomnia, or restless legs syndrome MAP \> 0.5 at screening
History or presence of any medical or neurological condition that could interfere with sleep (chronic pain, Restless leg, etc)
Current use of meds wth known psychotropic effects or known or suspected effects on sleep
Alcohol or substance abuse (unless in remission for at least a year
Excessive caffeine use (or any use after 6 pm for at least 3 months
Regular napping or any naps after 6 pm
Excessive cigarette or cigar smoking over the last 3 months
no participation in an investigational new drug study within 30 days of screening, and no previous participation in a study of PD200390
No night or rotating shift work
Clareo Health | Nonrestorative Sleep RSQ (Restorative Sleep Questionnaire) Development-- Methodology Study
