A Randomised, Double-Blind, Placebo-Controlled Study Assessing the Effect of Fenofibrate, Coenzyme Q10 and Their co-Administration on Ventricular Diastolic Function in Patients With Type 2 Diabetes

Exclusion Criteria

• •unable to comply with the protocol, Likely to leave the trial before completion
• •having participated in an another trial 3à days before V1
• •Pregnant or childbearing potential not using birth control method
• •Type 1 diabetic patients, T2Dm insulin therapy
• •Patients with one of the following pathology:
• •with muscular disorders known or increase CK , or hepatic deficiency or transaminase increase
• •with symptomatic gall-bladder disease or/and renal insufficiency
• •with abnormal thyroid function
• •with proliferative retinopathy
• •with recent cardiovascular event, uncontrolled hypertension
• •with known chronic alcohol intake
• •with other severe pathology
• •with TC\>= 7.0 mmol/L and/or TG\>= 4mmol/L at V1
• •Patients treated with Warfarin
• •Patients with specific ECG dysfunction