Evalution of Immunogenicity, Safety and Booster Response of a Rabies Vaccine Administered Concomitantly With Japanese Encephalitis Vaccine in Toddlers

Exclusion Criteria

• •a history of rabies immunization
• •a history of Japanese encephalitis immunization or disease
• •a significant acute or chronic infectious disease at the time of enrollment
• •fever ≥ 38.0°C (axillary) or/and significant acute or chronic infection requiring antibiotic or antiviral therapy within the past 7 days before enrollment
• •being under treatment with corticosteroids, immunosuppressive drugs or other specific anti-inflammatory drugs or having taken chloroquine during the two months period before enrollment
• •administration of any vaccine within the past 14 days before enrollment
• •known immunodeficiency or an autoimmune disease
• •history of allergy to eggs, egg products
• •known hypersensitivity to neomycin, tetracycline, amphotericin-B
• •planned surgery during the study period
• •being enrolled in any other investigational trial contemporaneously
• •the family plans to leave the area of the study site before the end of study period
• •history of febrile convulsions
• •history of wheezing