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COMPLETEDPhase 1NCT00692146

Study to Investigate the Effects Single Oral Dose of AZD1386 (Capsaicin)

A double-blind, randomized, single-centre, placebo-controlled, crossover study to investigate the effects of a single oral dose of AZD1386 on intradermal capsaicin evoked pain symptoms and heat sensit...

Lead sponsor: AstraZeneca•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

AstraZeneca

Age

20 - 45 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Clinical normal physical findings, including BP, pulse rate \>45 bpm, ECG and laboratory assessments
•Body Mass Index (BMI) of ≥18 to ≤30 kg/m2 and weight of ≥50 to ≤100 kg.
•Non-fertile females

Exclusion Criteria

•History of hypersensitivity, allergy or atopic/skin disease as judged by Investigator.
•History of somatic or psychiatric disease/condition, which may interfere with the objectives of the study as judged by the Investigator.

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: June 6, 2008Terms

Trial snapshot

StatusCOMPLETED

PhasePHASE1

Enrollment36

Start dateJan 2008

Last updatedJun 6, 2008

Condition

Capsaicin Evoked Pain Heat Sensitivity

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: June 6, 2008Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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