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A Pilot Study of Hypertension in Breast Cancer Patients Receiving Bevacizumab
This research study will look at the effect of an anti-angiogenesis medication called Bevacizumab on blood vessels. Anti-angiogenesis medicines fight cancer by cutting off a tumor's blood supply, starving the tumor of nutrients and oxygen. Previous studies have shown these types of drugs can cause hypertension. The purpose of this study is to help researchers better understand why these drugs cause hypertension. This information will assist researchers in learning how to control this side effect.
* Participants will begin this research study within 14 days of starting Bevacizumab, either as part of standard treatment or as part of another clinical trial. * Participants will have an ultrasound test done at baseline, and after completion of their first and second cycles of therapy. * Vital signs and blood tests will be performed a the start of the study, and after completion of the first and second cycles of therapy.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Dana-Farber Cancer Institute
Boston, Massachusetts, United States
Start Date
January 1, 2008
Primary Completion Date
September 1, 2010
Completion Date
September 1, 2010
Last Updated
May 6, 2014
10
ACTUAL participants
Bevacizumab
DRUG
Lead Sponsor
Dana-Farber Cancer Institute
Collaborators
NCT05245812
NCT05673200
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
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