Pre-Mix Insulin Lispro Treatment for Type 2 Diabetes Patients Who Consume a Light Breakfast

Inclusion Criteria

• •Diabetes Mellitus, Type 2
• •have been receiving metformin plus at least one other oral antihyperglycemic medication (OAM) (sulfonylurea or Thiazolidinedione \[TZD\]) without insulin, for at least 90 days prior to Visit 1
• •glycosylated hemoglobin (HbA1c) greater than or equal to 7.0% and less than 11.0%
• •regularly consume a light breakfast (less than 15% of total daily calorie intake)
• •capable and willing to follow the protocol
• •give written consent
• •have a body mass index greater than 40 kg/m\^2
• •have a history of severe hypoglycemia in past 24 weeks
• •are pregnant or may become pregnant
• •women who are breastfeeding
• •have significant cardiac disease
• •have significant renal or liver disease
• •undergoing therapy for a malignancy
• •contraindications to study medications
• •have an irregular sleep/wake cycle