Pregnancy

Intolerance to the study medication

Severe, unstable, active, or chronic inflammatory disease (active infection, active connective tissue disorder, active cancer, HIV, liver disease)

Type 1 Diabetes mellitus

Uncontrolled Type 2 Diabetes mellitus (HbA1c \> 10)

Hospitalization within 1 month prior to the study

Malfunctioning arterial-venous vascular access (recirculation and/or blood flow \< 250 ml/min)

Presence of hemodialysis catheter

Patients receiving steroids and/or other immunosuppressive agents (\> 10 mg prednisone qd)

BMI \< 25 and \> 45

Vitamin D, Insulin Resistance and Inflammation in ESRD