A Study of Pharmacokinetics and Safety of Alefacept in Caucasian and Japanese Healthy Volunteers

Exclusion Criteria

• •CD4+ lymphocyte count outside normal limits at Screening
• •Received vaccine within 60 days prior to study drug administration
• •History of drug or alcohol abuse within the 2 years prior to the study drug administration
• •Treatment with any systemic immunosuppressant agent within 6 months prior to study drug administration
• •Treatment with any antibody or biologic product within 6 months prior to study drug administration
• •Treatment with any systemic steroid or steroid inhaler within 2 months prior to study drug administration
• •A smoking habit of greater than 10 cigarettes a day