Analgesic Efficacy Of Valdecoxib In Patients Following Bunion Surgery

Exclusion Criteria

• •Patients who were scheduled to undergo other surgical procedures that would be expected to produce a greater degree of surgical trauma than the orthopedic procedure alone
• •Patients treated with patient controlled analgesia (PCA) subsequent to the end of anesthesia
• •Patients treated with long-acting local anesthetics or local anesthetics coadministered with epinephrine injected into the index joint space
• •Patients expected to require analgesics or other agents other than study medication during the 8 hours preceding administration of study medication through the end of the treatment period, that could confound assessment of the analgesic response, specifically excluded were tricyclic antidepressants, tranquilizers, neuroleptics, neuroleptic antiemetics, cyclooxygenase-2 inhibitors, nonsteroidal antiinflammatory drugs, and corticosteroids