Diclofenac Patch for Treatment of Mild to Moderate Tendonitis or Bursitis

Exclusion Criteria

• •Aspirin, or short half-life NSAID use within 12 hours, or longer half-life NSAID use within 24 hours prior to study entry (see Appendix B: for table of NSAIDs)
• •Opioid use within 3 days prior to study entry
• •Topical treatment, other than local ice or heat, applied to the painful region within 3 days prior to study entry
• •History of peptic ulcer disease within 1 year prior to study entry, any history of gastrointestinal bleeding, or coagulation disorder
• •A history of, or evidence for underlying articular disease such as osteoarthritis, rheumatoid arthritis, gout, or pseudogout (calcium pyrophosphate deposition disease)
• •Clinically significant and poorly controlled pulmonary, gastrointestinal, hepatic, renal, endocrine, or cardiovascular disease
• •A history of hypersensitivity to diclofenac or diclofenac-containing products
• •A history of intolerance to acetaminophen (rescue medication in this trial)
• •A history of skin sensitivity to adhesives (e.g. adhesive tape)
• •Pregnant or breastfeeding women and women of child-bearing potential not using effective means of contraception