Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Age
40–80
Sex
MALE
Healthy volunteers
Not accepted
You may be eligible if
Men aged 40 - 80 years old
Biopsy proven intermediate/high risk clinically localized prostate cancer, as determined by a Gleason score of 7 or higher, clinical stage T2b or higher, or PSA \> 10. Pathology will be confirmed by at least two reviews
Patients opting for EBRT (external beam radiation therapy, standard of care) without hormonal ablation
Ability to undergo serial TRUS procedures
Ability to give informed consent
You may not be if
Subject has known hypersensitivity to octafluoropropane.
Evidence of distant metastatic disease on staging evaluation
Previous treatment for prostate cancer, including any form of androgen ablation
Previous procedures involving the anus or rectum, making serial TRUS difficult or dangerous
Expected life expectancy less than 10 years
Baseline testosterone \< 200 ng/dL
Subject with cardiac shunts and elevated pulmonary hypertension
Subject has worsening or clinically unstable congestive heart failure.
Subject has acute myocardial infarction or acute coronary syndrome.
Subject has ventricular arrhythmias or is high risk for arrhythmias.
Subject has respiratory failure, severe emphysema or pulmonary emboli.
Subject has a history of cardiac shunt or pulmonary hypertension.
