Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Icahn School of Medicine at Mount Sinai
With
National Cancer Institute (NCI)
OBJECTIVES:
* Determine whether use of a contrast agent improves the images of the ovaries during ultrasonography.
OUTLINE: This is a multicenter study.
Patients may undergo baseline transabdominal or transvaginal ultrasonography, if not already done. Patients then undergo contrast-enhanced transabdominal or transvaginal ultrasonography using perflutren lipid microspheres (Definity®) IV.
Pathology reports from tissue collected during subsequent oophorectomy is analyzed and compared with ultrasonography findings.
Age
21–any
Sex
FEMALE
Healthy volunteers
Not accepted
You may be eligible if
DISEASE CHARACTERISTICS:
Diagnosis of adnexal mass
Scheduled to undergo surgical oophorectomy
PATIENT CHARACTERISTICS:
Not pregnant or nursing
Negative pregnancy test
No known respiratory failure as manifested by signs and symptoms of carbon dioxide retention or hypoxemia
No pulmonary vasculitis
No known history of severe emphysema
No known history of pulmonary emboli
No other condition that causes pulmonary hypertension due to compromised pulmonary arterial vasculature
No known history of severe pulmonary hypertension (i.e., systolic pulmonary artery pressures \> 90 mm Hg)
No known history of congenital heart defect that creates a bidirectional or right-to-left shunt
No worsening or clinically unstable congestive heart failure
No known acute myocardial infarction or acute coronary syndromes
No known serious ventricular arrhythmias
Not at high risk for arrhythmia due to prolongation of the QT interval
No known or suspected hypersensitivity to blood, blood products, or albumin
No known hypersensitivity to perflutren
No known or suspected hypersensitivity to octafluoropropane or any other ingredients of perflutren lipid microspheres (Definity®)
No mental status problems, illiteracy, or other circumstance that would preclude giving informed consent
PRIOR CONCURRENT THERAPY:
See Disease Characteristics
Clareo Health | Contrast-Enhanced Ultrasonography in Diagnosing Early-Stage Ovarian Cancer in Patients With an Adnexal Mass Undergoing Surgery to Remove the Ovary
