Prior treatment with chemotherapy

Operable patient with resectable tumour

Performance status \< 60 on the Karnofsky scale

A history of prior malignant tumour, except non-melanoma skin cancer or in situ carcinoma of the cervix and cured malignant tumour (more than 5-year disease free interval)

Polynuclear cells \< 2,000/mm³

Platelet cells \< 100,000/mm³

Serum bilirubin \>1.5 mg/100 ml

Serum creatinine \> 1.5 mg/100 ml and/or creatinine clearance \< 60 ml/min

Perception hypoacousia

Peripheral neuropathy

Recent myocardial infarction (less than 3 months prior to date of diagnosis)

Congestive cardiac failure requiring medical therapy or uncontrolled cardiac arrhythmia

Uncontrolled infectious disease

Serious medical or psychological factors which may prevent adherence to the treatment schedule

Randomised Study Comparing Three Chemotherapy Regimens in Non-small Cell Lung Cancer

What this study is about