Loading clinical trials...

COMPLETEDPHASE4

A Study Evaluating the Efficacy and Impact on Health-related Quality of Life of Levocetirizine in Adults With Seasonal Allergic Rhinitis

A Multi-center, Randomized, Double-blind, Placebo-controlled, Parallel-group Study Evaluating the Efficacy and Impact on Health-related Quality of Life of Levocetirizine 5 mg Once Daily Given for 2 Weeks in Subjects 18 yr of Age and Older With Seasonal Allergic Rhinitis

NCT00621959•UCB Pharma

View on ClinicalTrials.gov

Summary

The study objective is to investigate the efficacy of levocetirizine in reducing symptoms associated with seasonal allergic rhinitis and in improving rhinitis-related Quality of Life

Eligibility

Age

18 - 65 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Subjects with a history of SAR symptoms
•A positive skin prick test at least one grass allergen
•Moderate - severe SAR symptoms at baseline
•Women of childbearing potential must use a medically acceptable form of contraception
•80% compliance on run in study medication and 80% compliance on completing the diary

Exclusion Criteria

•The presence of any clinically significant comorbid disease which may interfere with the study assessments
•The presence of renal disease
•Pregnant or breastfeeding
•Subject is currently participating in another clinical trial
•Known hypersensitivity to piperazines or any of the excipients
•Intake of medications prohibited before the start of the trial
•Subjects who started or changed the dose of immunotherapy
•Rhinitis medicamentosa
•Subjects with a recent history (within the last 2 years) of drug or alcohol abuse.

Locations (26)

Scottsdale, Arizona, United States

Hot Springs, Arkansas, United States

Little Rock, Arkansas, United States

Huntington Beach, California, United States

Long Beach, California, United States

Los Angeles, California, United States

Mission Viejo, California, United States

Albany, Georgia, United States

Lilburn, Georgia, United States

Savannah, Georgia, United States

Key Dates

Start Date

March 1, 2008

Primary Completion Date

June 1, 2008

Completion Date

June 1, 2008

Last Updated

July 16, 2020

Enrollment

596

ACTUAL participants

Conditions

Seasonal Allergic Rhinitis

Interventions

levocetirizine dihydrochloride

DRUG

placebo

DRUG

A Study to Assess the Efficacy and Safety of PG-011 Nasal Spray in Adults With Moderate to Severe Seasonal Allergic Rhinitis

NCT06837233

Seasonal Allergic Rhinitis

View study

COMPLETEDPHASE1

A Clinical Pharmacology Study of MT-2990 in Seasonal Allergic Rhinitis Patients

NCT03570957

Seasonal Allergic Rhinitis

View study

COMPLETEDPHASE3

Efficacy and Safety of PQ Grass in Subjects With Seasonal Allergic Rhinitis and/or Rhinoconjunctivitis Induced by Grass Pollen

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: July 16, 2020Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

A Study Evaluating the Efficacy and Impact on Health-related Quality of Life of Levocetirizine in Adults With Seasonal Allergic Rhinitis

Inclusion Criteria

Exclusion Criteria

A Study to Assess the Efficacy and Safety of PG-011 Nasal Spray in Adults With Moderate to Severe Seasonal Allergic Rhinitis

A Clinical Pharmacology Study of MT-2990 in Seasonal Allergic Rhinitis Patients

Efficacy and Safety of PQ Grass in Subjects With Seasonal Allergic Rhinitis and/or Rhinoconjunctivitis Induced by Grass Pollen

Efficacy and Safety Study of Desloratadine (MK-4117) in Japanese Participants With Seasonal Allergic Rhinitis (MK-4117-204)

To Investigate Drug-drug Interaction and Relative Bioavailability Between the FDC AzelastineHCL/Beclomethasone Dipropionate Nasal Spray, & Beclomethasone Dipropionate Nasal Spray in the Test Vehicle, and RinoClenil® Nasal Spray

Efficacy and Safety of Azelastine +Mometasone , Nasal Spray, 140 mcg + 50 mcg, (Sandoz d.d., Slovenia) and Momat Rino Advance, Nasal Spray, 140 mcg + 50 mcg, (Glenmark, India) Administered as a Monotherapy to Patients With Seasonal Allergic Rhinitis.