Lead Sponsor

Johns Hopkins University

Collaborators

Age

18 - 50 years

Sex

FEMALE

Healthy Volunteers

Yes

•age greater than or equal to 18 years
•English-speaking
•ability and willingness to sign the informed consent
•ability and willingness to comply with the terms of the study
•voluntary request for pregnancy termination
•ultrasound-confirmed singleton intrauterine pregnancy with an estimated gestational age not exceeding 76 days (10 6/7 weeks) from the first day of the preceding menstrual cycle

•women who require or request sedation
•untreated acute cervicitis or pelvic inflammatory disease
•contraindications to lidocaine such as allergy to lidocaine, cardiac arrhythmia or heart block, and porphyria
•allergic reaction or sensitivity to lorazepam or NSAIDs
•chronic NSAID use
•history of gastritis or gastric ulcer
•acute renal failure or chronic renal disease
•chronic liver disease
•history of bleeding diathesis
•chronic narcotic use
•current or past history of illegal drug use (excluding marijuana)