Lead Sponsor

Mayo Clinic

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

•1. a. Suspected pancreatic adenocarcinoma, age 35 to 99 years.
•2. a. Chronic pancreatitis with chronic pain, age 18 to 99 years. Must be a confirmed diagnosis by either CT, endoscopic ultrasound (EUS), or endoscopic retrograde cholangiopancreatography (ERCP).
•2b. To undergo endoscopic or surgical decompression with 0 to 10 days of first study visit CT perfusion scan.
•2c. To answer pain questionnaire before first CT perfusion scan.
•2d. To return within three weeks to three months after decompression treatment for another CT perfusion scan and complete the second pain questionnaire.
•3a. Autoimmune pancreatitis, age 18 to 99 years either with diffuse or focal swelling of the pancreas confirmed by CT, MRI, or EUS or
•3b. Irregular narrowing of the pancreatic duct on ERCP and either elevated serum immunoglobulin G4 (IgG4), or histological confirmation.

•1a. Pancreatic ductal adenocarcinoma tumors with vascular involvement but without vascular occlusion.
•1. b. Pancreatic ductal adenocarcinoma tumors less than 2 cm in size.
•2. a. Chronic pancreatitis with diffuse and extensive pancreatic calcification.
•3. a. Autoimmune pancreatitis with a prior pancreas surgery or steroid treatment for autoimmune pancreatitis .
•Any Cohort:
•4\. Pregnant.
•5\. Prior iodine contrast reactions.
•6\. Iodine allergy.
•7\. Decreased kidney function being a serum creatinine greater than 1.5mg/dl.
•8\. Any contraindication to having a CT scan with iodine contrast.

Related studies

NCT02600949 · Metastatic Colorectal Adenocarcinoma, Metastatic Pancreatic Ductal Adenocarcinoma, and more

NCT06921928 · Gastric Cancer, Gastroesophageal Junction Cancer, and more

NCT06423326 · Borderline Resectable Pancreatic Ductal Adenocarcinoma, Resectable Pancreatic Adenocarcinoma, and more

NCT07542041 · Pancreatic Cancer, Pancreatic Neoplasms, and more

NCT06821997 · Borderline Resectable Pancreatic Ductal Adenocarcinoma

CT Pancreas Perfusion