Lead Sponsor

University of California, Davis

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

•Males or females 18 years of age or older.
•All female patients of childbearing potential must agree to use a medically accepted method of contraception at the time of the study.
•Patients must have the ability to understand the requirements of the study, provide written and informed consent to participate, and agree to abide by the study requirements.
•Patients who have known or suspected hydronephrosis or patients with solitary kidneys.

•Patients with known or suspected hypersensitivity to gadolinium-based agents.
•Patients who are pregnant or lactating.
•Patients with a condition that is a contraindication to MRI (e.g., cardiac pacemaker, epicardial pacemaker leads, cochlear implants, ferromagnetic aneurysm clip, ferromagnetic halo device, or other conditions that would preclude patient proximity to a strong external magnetic field).
•Patients with a recent history of hemolytic anemia, sickle cell anemia or other hemoglobinopathy.
•Patients with a history of significant claustrophobia.
•Patients with impaired renal function based on 24-hr urine collection (creatinine clearance \<10 ml/min or serum creatinine \>1.8 mg/dl)

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Functional, Dynamic, and Anatomic MR Urography