Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Yale University
With
University of Minnesota
Forest Laboratories
Age
21–75
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Clinical diagnosis of Pathological Gambling using the clinician-administered Structured Clinical Interview for Pathological Gambling (SCI-PG) (Grant et al., 2004);
Gambling behavior within 2 weeks prior to enrollment;
For women, negative results on a urine pregnancy test and stable use of a medically accepted form of contraception.
You may not be if
Infrequent gambling (i.e. less than one time per week) that does not meet DSM-IV criteria for PG;
Unstable medical illness or clinically significant abnormalities on laboratory tests, EKG, or physical examination at screen;
History of seizures;
Myocardial infarction within 6 months;
Current pregnancy or lactation, or inadequate contraception in women of childbearing potential;
A need for medication other than memantine with possible psychotropic effects or unfavorable interactions;
Clinically significant suicidality;
Current Axis I disorder determined by the SCID and SCID-compatible modules for impulse control disorders (Grant et al., 2005), except for nicotine dependence;
Lifetime history of bipolar disorder type I or II, dementia, schizophrenia, or any psychotic disorder determined by SCID;
Current or recent (past 3 months) DSM-IV substance abuse or dependence;
Positive urine drug screen at screening;
Initiation of psychotherapy or behavior therapy within 3 months prior to study baseline;
Previous treatment with memantine;
Treatment with investigational medication or depot neuroleptics within 3 months, with fluoxetine within 6 weeks, or with other psychotropics within 2 weeks prior to study baseline.
